4-CHLORO-5-(2-METHYLENE-BUTRYL)-INDOLE CARBOXYLIC

专利名称：4-CHLORO-5-(2-METHYLENE-BUTRYL)-INDOLE CARBOXYLIC ACID

发明人：JANOS ZERGENYI,ERNST HABICHT申请号：US3682961D申请日：19700819公开号：US3682961A公开日：19720808

摘要：The production of 5-(2-methylene-alkanoyl)-benzofuran-, 5-(2-methylene-alkanoyl)-indole- and 5-(2-methylene-alkanoyl)-benzo[b]thiophene-2-carboxylic acids byreaction of the corresponding 5-(2-dimethylaminomethyl-alkanoyl)- derivatives withsodium acetate in glacial acetic acid and their pharmaceutically acceptable salts withbases, a method of producing a diuretic and saluretic effect in mammals comprisingadministering said compounds to said mammals and pharmaceutical compositionscontaining said compounds are described. A typical embodiment is 5-(2-methylene-butyryl)-6-methyl-benzofuran-2-carboxylic acid.

申请人：CIBA-GEIGY CORP.

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